Pergunta clínica
Partimos de problemas relevantes para pacientes, profissionais e sistemas de saúde.
Pesquisa · Livros do grupo
Seis obras que traduzem a pesquisa em prática clínica.
Publicadas pela Artmed e pela Springer, em português e em inglês.
Vencendo a Depressão: Manual de Terapia Cognitivo-comportamental para Pacientes e Terapeutas
Braga, Vivan e PassosOnde obter
Psiquiatria Digital
Passos e GalloisOnde obter
Psicofármacos: Consulta Rápida, 6ª edição
Cordioli, Gallois e PassosOnde obter
Personalized Psychiatry: Big Data Analytics in Mental Health
Passos, Mwangi e KapczinskiOnde obter
Digital Mental Health: A Practitioner’s Guide
Passos, Rabelo-da-Ponte e KapczinskiOnde obter
Passo a Passo para a Vida: Superando o Comportamento Suicida
Aguiar, Shintani e PassosOnde obterMétodo
Dados só fazem sentido quando permanecem ligados às pessoas.
Nossa abordagem combina análise estatística tradicional, aprendizado de máquina e leitura clínica. A tecnologia é meio. O objetivo é compreender trajetórias, antecipar riscos e apoiar decisões melhores.
Desenho rigoroso
Escolhemos métodos adequados, protocolos transparentes e medidas clinicamente úteis.
Dados com contexto
Integramos informação clínica, sociodemográfica, biológica e digital.
Impacto verificável
Buscamos achados reprodutíveis que possam informar decisões e ampliar o cuidado.
Arquivo científico
120 artigos publicados entre 2012 e 2026.
O arquivo abre recolhido por ano. Toque em um ano para ver os artigos daquele período, ou filtre por tema. Cada referência abre a lista completa de autores e o registro no PubMed.
Prevalence and clinical correlates of cocaine use disorder among patients diagnosed with bipolar disorder: A systematic review, meta-analysis, and meta-regression
Digital interventions for depressive symptoms: a randomized clinical trial
Premorbid intelligence quotient and school failure as risk markers for bipolar disorder and major depressive disorder
Perinatal risk factors for the onset of bipolar disorder in young adulthood: a 22-year birth cohort
Exploring protective factors in a high-risk subsample: the pivotal role of paternal support in preventing depression in a cohort of young adults
Should we combine antipsychotics in patients with bipolar disorder?
Early exposure to cannabis and bipolar disorder incidence: Findings from a 22-year birth cohort study in Brazil
Protective factors against depression in high-risk children and adolescents: a systematic review of longitudinal studies
Prenatal and perinatal risk factors for bipolar disorder: A systematic review and meta-analysis
Psychopathological intersection between obsessive-compulsive disorder and post-traumatic stress disorder: scoping review of similarities and differences
Suicide risk classification with machine learning techniques in a large Brazilian community sample
Problematic Trading: gambling-like behavior in day trading and cryptocurrency investing
Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood
Hikikomori in Brazil: Context, clinical characteristics, and challenges
The Self-perception of Text message Dependence Scale (STDS): A Brazilian-Portuguese validation and expansion of its psychometric properties
Characteristics of deaths by suicide in postmortem studies in Brazil: A systematic review and meta-analysis
Withdrawal-like Symptoms in Problematic Pornography Use: A Scoping Review
Predicting functional impairment in euthymic patients with mood disorder: A 5-year follow-up
Is internet-based psychological therapy effective for treating major depressive disorder?
Validation of the Ten-Item Internet Gaming Disorder Test (IGDT-10) and Its Association with Functional Impairment in Brazilian Gamers
Treatment Approaches for Problematic Pornography Use: A Systematic Review
Examining the impact of the COVID-19 pandemic through the lens of the network approach to psychopathology: Analysis of the Brazilian Longitudinal Study of Health (ELSA-Brasil) cohort over a 12-year timespan
The Self-perception of Text message Dependence Scale (STDS): A Brazilian-Portuguese validation and expansion of its psychometric properties
Bipolar disorder treatment according to illness trajectory: a systematic review of clinical trials
Inflammatory and oxidative stress markers in post-traumatic stress disorder: a systematic review and meta-analysis
Predicting treatment response using EEG in major depressive disorder: A machine-learning meta-analysis
Systematic Review of Psychiatric Adverse Effects Induced by Chloroquine and Hydroxychloroquine: Case Reports and Population Studies
Differential impact in suicide mortality during the COVID-19 pandemic in Brazil
Predicting criminal and violent outcomes in psychiatry: a meta-analysis of diagnostic accuracy
Smartphone-based interventions in bipolar disorder: Systematic review and meta-analyses of efficacy. A position paper from the International Society for Bipolar Disorders ( ISBD ) Big Data Task Force
Classification of unipolar and bipolar depression using machine learning techniques
Prediction of suicide attempts in a prospective cohort study with a nationally representative sample of the US population
Precision Psychiatry: The Future Is Now
Pediatric bipolar disorder: Executive, linguistic, mnemonic, and cognitive efficiency mapping
Accelerated aging signatures in subjects with schizophrenia and their unaffected siblings
Loneliness, but not social distancing, is associated with the incidence of suicidal ideation during the COVID-19 outbreak: a longitudinal study
Prevalence and risk factors of psychiatric symptoms and diagnoses before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 mental health cohort
Neuroprogression in post-traumatic stress disorder: A systematic review
Evaluation of major depression symptom networks using clinician-rated and patient-rated data
Brazil
Differential power of placebo across major psychiatric disorders: a preliminary meta-analysis and machine learning study
Patterns of high-risk drinking among medical students: A web-based survey with machine learning
Association between childhood trauma, parental bonding and antisocial personality disorder in adulthood: A machine learning approach
Stigmatizing attitudes toward psychiatric disorders: A cross-sectional population-based survey
Psychometric Properties of the Nine-Item Problematic Internet Use Questionnaire in a Brazilian General Population Sample
From phone use to speeding and driving under influence: Identifying clusters of driving risk behaviors as an opportunity for targeted interventions
Early identification of bipolar disorder among young adults – a 22-year community birth cohort
Hikikomori and the COVID-19 pandemic: not leaving behind the socially withdrawn
Cariprazine for acute mood episodes in bipolar disorder
Predictors of suicide attempt in patients with obsessive-compulsive disorder: an exploratory study with machine learning analysis
Machine learning-guided intervention trials to predict treatment response at an individual patient level: an important second step following randomized clinical trials
Prediction of depression cases, incidence, and chronicity in a large occupational cohort using machine learning techniques: an analysis of the ELSA-Brasil study
Multimodal treatment for a Brazilian case of hikikomori
Prediction of attempted suicide in men and women with crack-cocaine use disorder in Brazil
Precision non- implantable neuromodulation therapies: a perspective for the depressed brain
The melancholic omega as sign of clinical depression and Darwin’s description of melancholy
Burnout in psychiatry residents: the role of relations with peers, preceptors, and the institution
Decoding rumination: A machine learning approach to a transdiagnostic sample of outpatients with anxiety, mood and psychotic disorders
The use of machine learning techniques in trauma-related disorders: a systematic review
Response to lithium has a neurobiological signature
Machine-learning approaches in psychotherapy: a promising tool for advancing the understanding of the psychotherapeutic process
Socio-demographic and psychiatric risk factors in incident and persistent depression: An analysis in the occupational cohort of ELSA-Brasil
Who attempts suicide among medical students? Acta Psychiatr Scand
Differential biomarker signatures in unipolar and bipolar depression: A machine learning approach
Bullying and psychotic symptoms in youth with bipolar disorder
Lower estimated intelligence quotient is associated with suicide attempts in pediatric bipolar disorder
Emotional memory in bipolar disorder: Impact of multiple episodes and childhood trauma
Machine learning and big data analytics in bipolar disorder: A position paper from the International Society for Bipolar Disorders Big Data Task Force
Clinical differences between patients with pediatric bipolar disorder with and without a parental history of bipolar disorder
Risk factors for suicidality in patients with panic disorder: A systematic review and meta-analysis
A risk calculator to predict adult attention- deficit/hyperactivity disorder: generation and external validation in three birth cohorts and one clinical sample – ERRATUM
Positive Predictive Values and Potential Success of Suicide Prediction Models
A risk calculator to predict adult attention- deficit/hyperactivity disorder: generation and external validation in three birth cohorts and one clinical sample
The prevalence and clinical correlates of cannabis use and cannabis use disorder among patients with bipolar disorder: A systematic review with meta-analysis and meta-regression
Adjunctive tianeptine treatment for bipolar disorder: A 24-week randomized, placebo-controlled, maintenance trial
Correction: Potential use of text classification tools as signatures of suicidal behavior: A proof-of-concept study using Virginia Woolf’s personal writings
Potential use of text classification tools as signatures of suicidal behavior: A proof-of-concept study using Virginia Woolf’s personal writings
Comorbid social anxiety disorder in patients with alcohol use disorder: A systematic review
Revisiting the Werther Effect in the 21st Century: Bullying and Suicidality Among Adolescents Who Watched 13 Reasons Why
Effects of valproate on brain volumes in pediatric bipolar disorder: A preliminary study
Volumetric brain magnetic resonance imaging predicts functioning in bipolar disorder: A machine learning approach
Risk Factors for Suicidality in Patients With Schizophrenia: A Systematic Review, Meta-analysis, and Meta- regression of 96 Studies
Neuron- glia Interaction as a Possible Pathophysiological Mechanism of Bipolar Disorder
Erratum to: Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study
Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study
The impact of machine learning techniques in the study of bipolar disorder: A systematic review
Brain gyrification and neuroprogression in bipolar disorder
Lifespan Gyrification Trajectories of Human Brain in Healthy Individuals and Patients with Major Psychiatric Disorders
Elevated Choline-Containing Compound Levels in Rapid Cycling Bipolar Disorder
Hippocampal subfield volumes in mood disorders
Peripheral biomarker signatures of bipolar disorder and schizophrenia: A machine learning approach
Changing the bipolar illness trajectory
Should bipolar disorder treatment be modified depending on staging? Expert Rev Neurother
Polycystic ovary syndrome and mental disorders: a systematic review and exploratory meta-analysis
Neuroprogression and illness trajectories in bipolar disorder
Increased BDNF levels after electroconvulsive therapy in patients with major depressive disorder: A meta-analysis study
Evidence of altered membrane phospholipid metabolism in the anterior cingulate cortex and striatum of patients with bipolar disorder I: A multi-voxel (1)H MRS study
Virginia Woolf, neuroprogression, and bipolar disorder
Reduced Neurite Density in Neuronal Cell Cultures Exposed to Serum of Patients with Bipolar Disorder
Clinical outcomes associated with comorbid posttraumatic stress disorder among patients with bipolar disorder
Areas of controversy in neuroprogression in bipolar disorder
Cognitive performance and psychosocial functioning in patients with bipolar disorder, unaffected siblings, and healthy controls
Individualized Prediction and Clinical Staging of Bipolar Disorders using Neuroanatomical Biomarkers
Post-traumatic stress disorder and interleukin 6 – Authors’ reply
Identification and individualized prediction of clinical phenotypes in bipolar disorders using neurocognitive data, neuroimaging scans and machine learning
The Comorbidity of Bipolar Disorder and Migraine: The Role of Inflammation and Oxidative and Nitrosative Stress
Identifying a clinical signature of suicidality among patients with mood disorders: A pilot study using a machine learning approach
Big data analytics and machine learning: 2015 and beyond
Individualized identification of euthymic bipolar disorder using the Cambridge Neuropsychological Test Automated Battery (CANTAB) and machine learning
Hippocampal volume and verbal memory performance in late-stage bipolar disorder
Predictors of psychiatric readmission among patients with bipolar disorder at an academic safety-net hospital
Inflammatory markers in post-traumatic stress disorder: a systematic review, meta-analysis, and meta- regression
Refractory bipolar disorder and neuroprogression
Immune activation as a mediator of the gut-brain axis in manic episodes
Developmental staging models in bipolar disorder
Differences in parental bonding between schizophrenia and bipolar disorder: Evidence of prodromal symptoms? Schizophr Res
The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders
Wet minds, dry minds, and the future of psychiatry as a science
Functioning in early and late stages of schizophrenia
Hypothyroidism and severe neuropsychiatric symptoms: a rapid response to levothyroxine